It's certainly true that the demonstration file for alcohol does cause a disorientating effect, though not one that's particularly pleasant. How realistic these are is tough to objectively assess, particularly given the legal, medical and ethical issues with running a control against the substances themselves. Others are blatantly labelled as recreating the experience of specific recreational drugs of varying legality. Some of these effects are simply conceptual such as being alert or calm, or even experiencing the emotions of first love. The claim is that this alters brainwaves, though scientists are skeptical to say the least. I-Doser uses specially crafted audio tracks that are designed to disorient the brain in a variety of manners using binaural beats, which mean that each ear hears sound at a different frequency. Just when you think you've seen everything that can be done on a computer, along comes something that's utterly unique.
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